Your weight impacts your hormones, immune system, and factors that regulate cell growth—all of which are tied to cancer risk. That’s why being overweight or obese may increase your chances of getting the disease. “The relationship between cancer and weight is complex, and several different mechanisms are involved,” Dr. Webster says. “According to research from the American Cancer Society, excess body weight is thought to be responsible for about 8 percent of all cancers in the United States, as well as about 7 percent of all cancer deaths.” Just avoid these 17 weight-loss “tricks” that don’t actually work.
After multivariate adjustment, including baseline RMR and dietary intervention group, baseline plasma PFAS concentrations, especially for PFOS and PFNA, were significantly associated with a greater decline in RMR during the weight-loss period (first 6 months) and a lower increase in RMR during the weight regain period (6–24 months). During the first 6 months, comparing the highest to the lowest tertiles, the least-square means (SEs) of RMR change were −45.4 (15.5) versus −5.0 (16.3) kcal/day for PFOS (Ptrend = 0.005) and −49.8 (15.9) versus −3.3 (16.1) kcal/day for PFNA (Ptrend = 0.002) (Model 3 in Table 4). During the period of 6–24 months, comparing the highest to the lowest tertiles, the least-square means (SEs) of RMR change were 0.9 (26.2) versus 94.6 (27.5) kcal/day for PFOS (Ptrend < 0.001); 12.7 (28.1) versus 69.3 (27.3) kcal/day for PFOA (Ptrend = 0.03); 24.6 (28.5) versus 81.5 (27.5) kcal/day for PFHxS (Ptrend = 0.03); 14.1 (27.7) versus 73.7 (27.6) kcal/day for PFNA (Ptrend = 0.02); and 23.1 (27.6) versus 66.5 (28.2) kcal/day for PFDA (Ptrend = 0.09) (Model 3 in Table 4). The results were similar when PFAS concentrations were treated as continuous variables (Table 4). When adjusting for RMR at 6 months (instead of RMR at baseline), the results maintained statistical significance. When changes in RMR or changes in thyroid hormones during the first 6 months were further adjusted for, the results remained largely unchanged. In the sex-stratified analysis, similar results were observed, although some associations did not reach statistical significance, possibly due to diminished power (S4 Table). No interaction between PFASs and sex on RMR changes was detected. The trajectory of changes in RMR among total participants according to tertiles of PFAS concentrations is shown in Fig 2. In addition, similar results were demonstrated when analyses were stratified by dietary intervention group.
The next time you’re making a salad, why not throw some watercress in there? The green veggie is an excellent source of folate, which has been shown to stimulate weight loss. In fact, a study in the British Journal of Nutrition found that those with the highest folate levels lose about 8.5 times more weight when dieting than those with the lowest levels of folate. What’s more? A separate study in the British Journal of Cancer found that higher dietary folate intake reduces the breast cancer risk. In addition to watercress, other good sources of folate include spinach, asparagus, and papaya.
It's truly disturbing when doctors come up with seemingly fad diets that could prove dangerous, but that appears to be happening all the time and most of them are also pretty successful. The latest to join the trend is an American doctor who is providing a drastic and quick weight-loss method, the K-E Diet. It involves putting food into your body through the nose, using a dripping tube.