Perfluoroalkyl substances (PFASs), especially perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS), have been identified as plausible endocrine disruptors with the potential to perturb weight regulation [9,11–14]. Evidence from animal studies has suggested that PFASs may be involved in altering energy metabolism and thyroid hormone homeostasis [15–17], likely through the activation of various transcriptional factors, such as the peroxisome proliferator-activated receptors (PPARs) [18–20]. However, given the species-specific toxicokinetics and tissue distribution of PFASs [18], extrapolation from animals to humans has yet to be supported. Although some human studies have examined the potential intergenerational effects of PFASs on body weight, the findings were somewhat inconsistent [21–27]. To our knowledge, no prospective study has explored the association between PFAS exposure and weight change in adults under controlled circumstances. Furthermore, it is largely unknown whether resting metabolic rate (RMR) or thyroid hormones, factors that can influence energy expenditure [28], might be also involved in the potential effects of PFASs on weight regulation [29,30].
It's a one-time investment you'll never regret. Here's why: Strength training builds lean muscle tissue, which burns more calories — at work or at rest — 24 hours a day, seven days a week. The more lean muscle you have, the faster you'll slim down. How do you start strength training? Try some push-ups or a few squats or lunges. Use your free weights to perform simple bicep curls or tricep pulls right in your home or office. Do these exercises three to four times per week, and you'll soon see a rapid improvement in your physique. 

Common sense states if you want to lose weight, then you shouldn’t have a large meal not long before going to bed. And now we have additional research to back up that hypothesis. A study published in the journal Obesity followed two groups of overweight women with metabolic syndrome on identical 1,400-calorie weight loss diets for three months. While both groups consumed 500 calories at lunch, one group consumed 700 calories for breakfast and a 200-calorie dinner (the “big breakfast” group), while the other group ate 200 calories at breakfast and 700 calories at dinner (the “big dinner” group). Even though the nutrient content of the meals was exactly the same for both groups, after three months the big breakfast group lost about two and a half times more weight than big dinner group.
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Unfortunately, metabolic compensation isn’t your body’s only strategy to prevent weight loss or encourage weight gain. Hunger hormones – leptin and ghrelin – are also at play. Fat cells produce leptin, which tells your brain when you’re full. Fat cells also shrink when you lose weight, producing less leptin and meaning you don’t feel as full. Strike one. Ghrelin, produced by the stomach, tells the brain it’s time to refuel. When you lose weight, ghrelin levels rise, prompting you to want to eat more frequently. Strike two. Research suggests that neither leptin levels nor ghrelin levels return to a normal baseline for at least a year.
During the 3 days of the diet, balanced nutrition is lacking. Some of the foods that are recommended are high in salt and fat and would not be appropriate for people with certain medical problems like heart disease, high blood pressure, diabetes, or high cholesterol. You may not be getting enough vitamins, minerals, and fiber while you are on the diet. If you are taking medicine for your diabetes and want to try the 3-day diet, it's important to talk with your doctor first about how to adjust your medicine.
Weight loss can be intentional, such as from dieting and exercise, or unintentional and be a manifestation of illness. Weight loss can result from a decrease in body fluid, muscle mass, or fat. A decrease in body fluid can come from medications, fluid loss, lack of fluid intake, or illnesses such as diabetes. A decrease in body fat can be intentionally caused by exercise and dieting, such as for overweight or obesity. Weight loss is normal after pregnancy. Other causes of weight loss include, but are not limited to, cancer, viral infection (such as CMV or HIV), gastroenteritis, parasite infection, depression, bowel diseases, and overactive thyroid (hyperthyroidism).

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Driving to work may be easy, but it’s also part of what’s inhibiting you from losing weight. According to a study in the British Medical Journal, those who drive to work gain more weight than those who take public transportation. Per the research, commuting by car slaps an extra 5.5 pounds on your body, whether you exercise or not. And a Japanese study found that people who take public transportation to work were 44 percent less likely to be overweight, 27 percent less likely to have high blood pressure, and 34 percent less likely to have diabetes. If possible, consider leaving the car in the driveway and walking, biking, or commuting to work via public transportation a few times per week.

Coffee jumpstarts your metabolism, making the non-decaf stuff a worthy weight loss ally. According to a study published in the journal Physiology & Behavior, the average metabolic rate of people who drank caffeinated coffee was 16 percent higher than that of those who drank decaf. And remember, don’t ruin your fat-blasting cup of joe by adding any unhealthy creamers and/or artificial sweeteners to it, both of which are enemies of weight loss.
I see so many people posting photos of awful boring meals.. Eating dry chicken and dry potatoes every night is soon going to get boring.. and let’s face it! That is when we end up going off of plan and giving up.. boring diets=failure. I save all of my Slimming World magazines and I follow loads of blogs. So each week I look for new recipe ideas. I actually quite enjoy suggesting things to my husband and him kind of screwing his nose up at it.. but when it is served up to him he loves it (usually).
You can make alterations to this ratio depending on what foods you like, how your body responds, and your daily activity level. If you'd rather, you can change this ratio to make 30 percent of your calories from fat, 30 percent from carbs, and 40 percent from protein. Or, you can do a 20/30/50 split. The idea here is that macronutrient distribution does not follow a "one size fits all" template.
Hiley Fulgence is a professional Personal Trainer, Nutritionist, and Sports Massage Therapist who has worked around the world helping people to improve their fitness, achieve better overall health, and maximize their performance. At the BodyHoliday, he specializes in nutrition for weight loss, assessment and treatment for injury prevention and rehabilitation, and sports science testing & performance enhancement. As a former track and field athlete, he brings a unique enthusiasm and compassion, along with the determination to improve his clients’ physical wellbeing.

Why it's dangerous: Arsenic is highly toxic in its inorganic form and in high doses. According to the World Health Organization it can also cause health problems such as skin lesions and cancer when consumed through food or drinking water. The symptoms of arsenic poisoning include vomiting, nausea, diarrhoea, severe muscle cramping and even death. It's certainly not a substance you would want in medication. 


Real talk: It could take weeks or months to see the metabolic effects of exercise on the scale, and even then, building muscle, which is denser than body fat, could lead to weight gain. “Do what you like because it’s good for you,” Dr. Seltzer says, noting the way exercise is awesome for your heart, mental health, and more—and that not all measure of progress can be seen on the scale.

Make sure that everything you're eating is whole — as in nothing processed or packaged. Since salt is a preservative, these are the foods that are highest in sodium — something to keep in mind when planning your meals. Plan on making sure that all items you choose are fresh. That means filling up on fresh fruits and veggies, whole grains, low-fat dairy, and lean protein.


Did bikini season sneak up on you? Is your soon-to-be worn wedding dress still just a touch too tight? Did a last-minute invite for a beach getaway come your way? You're a lucky dog – and a panicked one too because you want to drop pounds, and fast. These 10 diets are likely to help you lose significant weight within a year, according to a panel of experts who reviewed 38 plans for the U.S. News Best Diets rankings. Just remember: Short-term weight loss is markedly different from long-term weight loss, which is more important for your health.
A healthy weight loss program should never be about dieting alone. It should be a balanced approach including nutrition that’s right for your metabolism, sensible exercise, food preparation management and the right mindset.  This retreat embodies that holistic approach, with personalized tools to get your weight to where you want it to be and continued support with weight management thereafter. Your pre-arrival consultation will guide our team of nutritionists, chefs, personal trainers, physiologists and instructors, to prepare your bespoke plan of action and help you execute it.
In an analysis stratified by sex, significant associations with weight regain were observed for all individual PFASs in women, but not in men. Comparing the highest to the lowest tertiles, the least-square means (SEs) of weight regain in women were 4.0 (0.8) versus 2.1 (0.9) kg for PFOS (Ptrend = 0.01); 4.3 (0.9) versus 2.2 (0.8) kg for PFOA (Ptrend = 0.007); 4.9 (0.9) versus 2.7 (0.8) kg for PFHxS (Ptrend = 0.009); 4.7 (0.9) versus 2.5 (0.9) kg for PFNA (Ptrend = 0.006); and 4.2 (0.8) versus 2.5 (0.9) kg for PFDA (Ptrend = 0.03) (Table 3). Significant interactions with sex were demonstrated for PFOA and PFHxS (Pinteraction = 0.04 and 0.01, respectively). When the covariates were entered into the model in a stepwise manner, these results did not change materially (S3 Table). The trajectory of changes in body weight in men and women according to tertiles of PFAS concentrations is shown in Fig 1. The trajectory of changes in body weight among total participants is shown in S1 Fig.
“ Your waistline is important to your health with the fat around your waist being metabolically active ,” said Holly S. Andersen, M.D., Attending Cardiologist, Director of Education and Outreach at the Perelman Heart Institute, Clinical Associate Professor of Medicine (Cardiology) Joan and Sanford I. Weill Cornell Department of Medicine, New York Presbyterian Hospital. “This type of fat (visceral fat) makes your blood pressure and lipid (cholesterol) levels less favorable, makes you more prone to insulin resistance and diabetes, and is ‘pro-inflammatory’ with inflammation being the gateway to disease:  brain disease, heart disease and cancer.”
Is your obsession with Reese’s and Pringles derailing your weight loss efforts? It might be if you’re not using the self-checkout kiosks at the grocery store. Let us explain: According to a study by IHL Consulting Group, impulse purchases dipped 32.1 percent for women and 16.7 percent for men when they scanned their items and swiped their credit card on their own. Although not all impulse buys are bad for your belly, a whopping 80 percent of candy and 61 percent of salty-snack purchases are unplanned. 

Cilantro, though polarizing in terms of taste, contains a unique blend of oils that work much like over-the-counter meds to relax digestive muscles and alleviate an “overactive” gut. A study published in the journal Digestive Diseases and Science found that patients with IBS benefited from supplementing with cilantro as opposed to a placebo because their bellies weren’t as bloated.
Belly Fat! Without doubt, one of the most common and dangerous types of fat. Losing it is not only important from an aesthetic point of view but it's also essential for health reasons. Excessive abdominal fat, also referred to as visceral fat, can form within your abdomen between your organs and secrete proteins that can potentially lead to type 2 diabetes, heart disease and some cancers. There's good news though - losing this fat is easier than most people think as long as they have the correct advice. Our latest FREE ebook offers 81 tips to lose this stubborn form of fat.

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The least intrusive weight loss methods, and those most often recommended, are adjustments to eating patterns and increased physical activity, generally in the form of exercise. The World Health Organization recommended that people combine a reduction of processed foods high in saturated fats, sugar and salt[10] and caloric content of the diet with an increase in physical activity.[11]

One weight loss counselor who offers the program said it's not the urine, but the hormone in it that takes off the pounds. “It's human chorionic gonadotropin,” said Iris McCarthy of Success Weight Loss Systems. She said hCG tricks your brain into thinking your body is pregnant. McCarthy said science has shown her hCG helps the body metabolize faster. “This will help you have patience to learn how to change your ways and change your relationship with food,” said McCarthy. 

Losing weight is a lot more than calorie counting and doing endless amounts of exercise. Although these things help, in reality it's a little more complicated. If you're feeling stuck in a weight-loss rut there are plenty of expert tips and industry secrets to help you on your way. Whether you want to make your workouts work harder for you or find smarter ways of eating healthily, this list of 30 ways to slim down faster should help you toward your goal.
The bigger your plate, the bigger your meal, Brown reminds us. How so? While smaller plates make food servings appear significantly larger, larger plates make food appear smaller—which can lead to overeating. In one study, campers who were given larger bowls served themselves and consumed 16 percent more cereal than those given smaller bowls. Swapping dinner for salad plates will help you eat more reasonable portions, which can help the pounds fly off your frame! To kick even more calories to the curb, use small red plates. Although the vibrant hue may not match your dining room decor, the color can help you eat less, according to a study published in the journal Appetite. Researchers suggest that the color red reduces the amount we’re likely to eat by subtly instructing the mind to stop noshing.
If you just can’t shake those belly-bloating sugar cravings, try tyrosine—a building block of protein. It has been shown to prevent that yearning for the sweet stuff by encouraging the brain to release dopamine and another neurotransmitter, norepinephrine. In other words, eating more tyrosine (which can be found in eggs, spirulina, certain cheeses such as Parmesan, Gruyère, Swiss, and Romano, milk, sesame seeds, beef, and bacon) helps fend off those harmful sugar cravings that make your belly fat.
It’s every chocoholic’s dream: Research now shows that eating moderate amounts of dark chocolate can reduce overall body fat and shrink your waist. A study among women with normal weight obesity (or skinny fat syndrome) who ate a Mediterranean diet that included two servings of dark chocolate each day showed a significant reduction in waist size than when on a cocoa-free meal plan. Researchers say it has to do with the flavonoids, heart-healthy compounds in chocolate that have important antioxidant and anti-inflammatory properties. Just be sure you’re reaching for a bar with at least 70 percent cacao, and stay away from the “alkalized” stuff, which has a significantly reduced flavonoid content.
“Repetition builds rhythm. Be boring. Most successful losers have just a couple of go-to breakfasts or snacks,” says registered dietitian Lauren Slayton. “Make an effort to pinpoint these for yourself. ‘Hmm, I’m starving what should I have?’ doesn’t often end well. You can change the rotation every few weeks, but pre-set meals or workouts on certain days will help tremendously.”
VLCDs are doctor-supervised diets lasting several weeks. The meals are nutritionally balanced, but expensive -- people can end up spending thousands of dollars over time. VLCDs safely produce a loss of 15% to 25% of body weight in 12 weeks. That's for those who finish the program: 25% to half of people don't complete the program. Weight returns when the diet is stopped and happens rapidly; some experts say its best to take a more sustainable approach to weight loss comparable to that of regular diets.

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Lord Byron wasn’t only famous for his poems and politics, but also for popularising the vinegar diet in the 1820s. The idea is simple – drink plenty of vinegar, paired with one cup of tea and a raw egg. This combination made you vomit, causing you to lose your appetite, and weight. The legacy lives on in the claim that apple cider vinegar can make you lose weight.
Tart cherries are grown exclusively in Michigan, but if you’re able to get your hands on them there is strong evidence to suggest they can help you achieve your weight loss goals. Need proof? Researchers at the University of Michigan conducted a 12-week study that found that rats fed tart cherries showed a 9 percent belly fat reduction over those fed a standard western diet. Scientists believe this is because tart cherries are especially high in anthocyanins, a type of flavonoid with strong antioxidant activity. These and other flavonoids found in tart cherries have also been shown to have anti-inflammatory effects.
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A talented staff on the cutting edge of fitness and healthy living teaches guests the latest in wellness thinking: keep moving; eat real food; cultivate connections. They debunk the "calories in-calories out"  myths, i.e., the only way to lose weight is to eat fewer calories and exercise more. In fact, compulsive over-exercising might just be undermining your health. 

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Are you considering a visit to a weight loss resort? Many smart dieters begin their journey away from home to get a clean break from the habits and lifestyle practices that led to weight gain in the first place. It's a smart approach if you can afford the luxury, but a visit to a health spa is not cheap, so it's smart to do your homework before you decide where to go.
All package rates are quoted per person based on double deluxe accommodations and are subject to availability. High season, weekends and holidays may be higher. When purchasing a wellness package, early departures will be assessed at 100%. Room tax not included. Villa suites and single occupancy are available at higher rates. Spa treatments, when included in a package, cannot be substituted. Substitutions will void package price. Twenty-four-hour notification is required for all cancelled or changed appointments to avoid a 50% cancellation fee. Missed appointments will be forfeited and charged at full price. Offers are not valid in conjunction with any other discount, promotional event or seasonal special. Spa & salon services, golf, outdoor adventure trips & Wellness Center services can be added to any package foran additional fee.
If you're a European or English yogi, then you can easily stay close to home for your get-into-shape holiday. This makes it much easier to incorporate everything you learn into your new, healthy life. Plus, you are close enough to the retreat that you might meet a few friendly neighbors. And isn't that so cool that you can build a health-focused community so easily?
Celebrating our 27th year in business, Tennessee Fitness Spa offers a fully equipped gym, heated swimming pool, fitness class room, cycling room, racquetball court, sauna, hot tub, sun deck, dining hall, beauty salon, massage rooms, T.V. lounges, and accommodations for 58 people. We are a full-service weight loss retreat that is surprisingly affordable and proven to be effective.
At any given time, there are dozens of weight-loss hypes in the marketplace that claim to take off 10 pounds in 10 days, or whatever. Desperation can tempt us to try anything — from "clean eating" to cutting out food groups entirely. Keep in mind: Just because an avocado-walnut-"crunchy"-kale-salad dripping in coconut oil is deemed "clean" by a so-called "expert" on your Instagram feed does not make it an unlimited food. Moral of the story? Avoid fads, eat real food, watch some Netflix, and unwind (perhaps with a glass of wine in hand). Now that's my kind of detox.
Start each morning with a sunrise stretch, cooking class or medical lecture and finish the day with Tai Chi, a stress management class or a night out in South Beach. This Miami resort, surrounded by 650 acres of gardens, fountains and water features, focuses on “real world training” so that guests can apply what they’ve learned at home. The health facility features an indoor track, two restaurants that offer gourmet meals (think Maine lobster and wild mushroom risotto), pools, five golf courses, a spa, and a tennis court. Take advantage of the resort’s personal training sessions, counseling and educational courses as well. The all-inclusive resort offers a one-week (starting at $3,600) and two-week program (starting at $6,200).
VLCDs are doctor-supervised diets lasting several weeks. The meals are nutritionally balanced, but expensive -- people can end up spending thousands of dollars over time. VLCDs safely produce a loss of 15% to 25% of body weight in 12 weeks. That's for those who finish the program: 25% to half of people don't complete the program. Weight returns when the diet is stopped and happens rapidly; some experts say its best to take a more sustainable approach to weight loss comparable to that of regular diets. 

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* Results are not guaranteed. Results will vary based on each patient’s physical health, family history, diet and exercise, physical condition and adherence to the One Body program. The weight loss results described herein may or may not be typical. References to “losing inches” or “inches lost” means total combined inch loss from the waist, hips and thighs. No prescriptions or treatments (including testosterone injections) will be given unless a clinical need exists based on an examination, any necessary testing or labs, a medical consultation and current medical history.
Great question, Cain. The cumulative stress of training for a competition and then cutting 10-20 pounds certainly does compromise the immune system. (So does competition itself, for a few hours after the event). Then, when you stuff hundreds of people in an arena or auditorium, all sharing their bacteria and viruses with those compromised immune systems…so getting a cold is the very common. All big athletic events are like this: marathons, tournaments, etc.
The bigger your plate, the bigger your meal, Brown reminds us. How so? While smaller plates make food servings appear significantly larger, larger plates make food appear smaller—which can lead to overeating. In one study, campers who were given larger bowls served themselves and consumed 16 percent more cereal than those given smaller bowls. Swapping dinner for salad plates will help you eat more reasonable portions, which can help the pounds fly off your frame! To kick even more calories to the curb, use small red plates. Although the vibrant hue may not match your dining room decor, the color can help you eat less, according to a study published in the journal Appetite. Researchers suggest that the color red reduces the amount we’re likely to eat by subtly instructing the mind to stop noshing. 

Did bikini season sneak up on you? Is your soon-to-be worn wedding dress still just a touch too tight? Did a last-minute invite for a beach getaway come your way? You're a lucky dog – and a panicked one too because you want to drop pounds, and fast. These 10 diets are likely to help you lose significant weight within a year, according to a panel of experts who reviewed 38 plans for the U.S. News Best Diets rankings. Just remember: Short-term weight loss is markedly different from long-term weight loss, which is more important for your health.

Believe it or not, weight loss isn’t just about exercising and eating right; research suggests what motivates you to get in shape can play a role in your success. A 2014 study in the journal Body Image looked at 321 college-age women and found that long-term, those who exercised primarily for appearance-based reasons had a harder time sticking to their fitness plans than those who worked out to maintain their health. In other words, stop envying those fit models on Instagram and instead remember that you and your loved ones are the people who really benefit when you slim down.
Sleep apnea, in which you actually stop breathing during sleep, is linked with being overweight or obese. “Sleep apnea is caused, in part, when extra tissue accumulates around the upper airway, which can change its shape and make the throat more likely to collapse during sleep,” says sleep expert Richard Shane, PhD, creator of the Sleep Easily method. In one study, 88 percent of people who lost 33 or more pounds were effectively cured. According to Harvard Medical School, losing just 10 percent of your body weight can drastically reduce sleep apnea symptoms—and in some cases, weight loss can even cure the condition. Don’t miss these other signs your weight gain means your health is in trouble.
First things first: Whether you do or don't want to lose weight is totally personal; if you want to, great, but if you don't, that is perfectly fine as well. If weight loss is one of your goals this year and you don't know where to start, you're not alone. Nearly a quarter of the Americans who resolve to change something about their lives this New Year’s will be hoping to shed some pounds—and preying on these doe-eyed resolvers will be all manner of “fast weight loss solutions.” They’ll guarantee instantaneous results or promise to make the pounds melt off without you having to change a thing. The reality is, losing weight in a safe, healthy, and effective way is a lot more complicated than that.
As chronic obstructive pulmonary disease (COPD) advances, about 35% of patients experience severe weight loss called pulmonary cachexia, including diminished muscle mass.[31] Around 25% experience moderate to severe weight loss, and most others have some weight loss.[31] Greater weight loss is associated with poorer prognosis.[31] Theories about contributing factors include appetite loss related to reduced activity, additional energy required for breathing, and the difficulty of eating with dyspnea (labored breathing).[31]
Everyone at the retreat is on the same journey. Everyone is equally committed to improving themselves, even if their stories are different than yours. Whether you bond over the process of taking the plunge, the difficulty in switching your diet, the aches and pains that come with a new yoga routine, or the grumbles that you maybe received from loved ones back home…

Tart cherries are grown exclusively in Michigan, but if you’re able to get your hands on them there is strong evidence to suggest they can help you achieve your weight loss goals. Need proof? Researchers at the University of Michigan conducted a 12-week study that found that rats fed tart cherries showed a 9 percent belly fat reduction over those fed a standard western diet. Scientists believe this is because tart cherries are especially high in anthocyanins, a type of flavonoid with strong antioxidant activity. These and other flavonoids found in tart cherries have also been shown to have anti-inflammatory effects.
Berries are more than just morsels of sweetness that you can toss on yogurt or work into a smoothie; they can help you lose weight, too! Raspberries pack more fiber and liquid than most other fruits, which boosts satiety. They’re a rich source of ketones, antioxidants that can make you slimmer by incinerating stored fat cells. And like other berries, raspberries are loaded with polyphenols, powerful natural chemicals that have been shown to decrease the formation of fat cells and eliminate abdominal fat. Not to be outdone, research suggests blueberries can also help blast away stubborn belly fat by engaging your get-lean genes. After a 90-day trial, University of Michigan researchers discovered rats that were fed a blueberry-enriched diet showed significantly reduced belly fat compared to those who skipped the berries.
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Stavrou, S., Nicolaides, N. C., Papageorgiou, I., Papadopoulou, P., Terzioglou, E., Chrousos, G. P., … Charmandari, E. (2016, July 31). The effectiveness of a stress-management intervention program in the management of overweight and obesity in childhood and adolescence. Journal of Molecular Biochemistry, 5(2), 63–70. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996635/

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This resort is tailored specifically for women in need of a mind, body, and soul rejuvenation. Through its variety of programs, Green Mountain emphasizes a non-diet approach and aims to instill a new way of thinking into its guests. The resort, which houses only 40 to 45 women at a time, has earned a spot on SpaFinder’s readers’ choice list of Best Weight Loss for Women for nine consecutive years. Most of its programs are based off of a four-week curriculum, but guests can choose to stay one week at a time. The facility’s 12-week “Train Your Brain” program ($25,000 for triple accommodation) is also available for women in need of a more intense program. Guests can add on targeted tracks for extra support with issues such as binge eating, Polycystic Ovary Syndrome, diabetes and more.

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